The intensity of cultural and humanitarian cooperation is low due to the geographical remoteness of the countries and the lack of historical ties.

In 2018 delegation of the Women's Union of Ukraine visited Cambodia working with representatives of the Cambodian Women for Peace and Development.

In 2022 and 2023 two public lectures dedicated to the Russian aggression against Ukraine were held at the Cambodian Institute for Cooperation and Peace.

Since 2023, Ukraine has been participating in the annual European Union Film Festival in Cambodia.

In 2023 the training program for Ukrainian demining specialists was launched in Cambodia, jointly conducted by the Cambodian Mine Action Center and the Japan International Cooperation Agency.